BIOST 578A - University of Washington: Spring, 2013

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Scott S. Emerson, M.D., Ph.D.
Professor of Biostatistics
Department of Biostatistics
University of Washington

Special Topics: Statistical Design of Randomized Clinical Trials
This course will address issues related to the statistical design of clinical trials, including such topics as selection of statistical estimand; randomization strategies, including dynamic balancing and response adaptive randomization; group sequential sampling rules, including both frequentist and Bayesian approaches; adaptive sampling rules, including response adaptive re-powering of RCT and enrichment; and approaches to addressing missing data in RCT.

Instructor:Scott S. Emerson, M.D., Ph.D.




Office:HSB F673
Office Hours:by appointment

Times and Places
Lectures : MW 8:00am - 9:20am HST 663

Syllabus and General Information
BIOST 578A Syllabus (pdf)

R Materials
Access to RCTdesign

Day  Date   HandoutsVideosHW AssignedHW DueMiscellaneous
MonApr 1 Lecture 1 Lecture      
WedApr 3   Lecture      
MonApr 8 Lecture 2 Lecture      
WedApr 10   Lecture HW #1      
MonApr 15   Lecture      
WedApr 17   Lecture      
MonApr 22 Lecture 3 Lecture HW #2      
WedApr 24   Lecture      
MonApr 29   Lecture      
WedMay 1   Lecture      
MonMay 6   Lecture HW #3      
WedMay 8   Lecture